Posts Tagged ‘male’

Stories of people getting more testosterone and coming to regret it. And of people losing it and coming to appreciate life without it. The pros and cons of the hormone of desire. – See more at: http://www.thisamericanlife.org/radio-archives/episode/220/testosterone#sthash.1xSaFmPK.dpuf

By: Larry Cahill, Ph.D.

Early in 2013, the Food and Drug Administration (FDA) ordered the makers of the well-known sleep aid Ambien (zolpidem) to cut their recommended dose in half-but only for women. In essence, the FDA was acknowledging that despite extensive testing prior to the drug’s release on the market, millions of women had been overdosing on Ambien for 20 years. On February 9, 2014, CBS’s 60 Minutes highlighted this fact-and sex differences in general-by powerfully asking two questions: Why did this happen, and are men and women treated equally in research and medicine?1

The answer to the first question is that the biomedical community has long operated on what is increasingly being viewed as a false assumption: that biological sex matters little, if at all, in most areas of medicine. The answer to the second question is no, today’s biomedical research establishment is not treating men and women equally. What are some of the key reasons for the biomedical community’s false assumption, and why is this situation now finally changing?  What are some of the seemingly endless controversies about sex differences in the brain generated by “anti-sex difference” investigators?  And what lies at the root of the resistance to sex differences research in the human brain?

– See more at: http://www.dana.org/Cerebrum/2014/Equal_%E2%89%A0_The_Same__Sex_Differences_in_the_Human_Brain/#sthash.lKD5UT9i.dpuf

New Study Compares Male-Only and Female-Only Trials to Mortality Rates

Contrary to longstanding public perception, women do not appear to be under represented or understudied in scientific clinical research trials in the United States, according to a new study by researchers at the Johns Hopkins University Bloomberg School of Public Health. The findings were most pronounced among cancer related clinical trials. The researchers concluded that women are represented in twice as many cancer trials compared to men, even though men die more frequently from the disease and often die at an earlier age. The study is the first to quantify gender bias in clinical research. Researchers measured the levels of bias by comparing male-only and female-only trials with death rates for each sex from heart disease, malignant cancer, and other causes. The findings appear in the April 30, 2001 edition of Statistics in Medicine.

“The findings are important because the perception that females are under represented and their diseases are understudied erodes the public trust, which is essential to continued clinical research,” says Curtis L. Meinert, PhD, professor of epidemiology and director of the Center for Clinical Trials at the Johns Hopkins University Bloomberg School of Public Health.

For years, policy makers and the general public have assumed that medical research favored men over women. The perception was so compelling that Congress enacted legislation in 1993 explicitly requiring the inclusion of women in clinical trials.

(Continue Reading...)